drugset / Trial / NCT03987295

A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

NCT03987295

Phase 2 Completed 33 enrolled Alector Inc. GlaxoSmithKline · collab
NaSingle-groupOpen-labelTreatment

Summary

A Phase 2 open label study evaluating the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AL001 in participants with a Granulin mutation or C9orf72 mutation causative of frontotemporal dementia.

Timeline

Start
2019-09-27
Primary completion
2024-06-05
Completion
2024-06-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Latozinemab Monoclonal antibody 60 mg/kg Intravenous