drugset / Trial / NCT04001894

Ticagrelor and Clopidogrel on Platelet Effects in Chinese Patients With Stable Coronary Artery Disease

NCT04001894 ↗

RandomizedCrossoverSingle-blindTreatment

Summary

Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor reduces thrombotic events in patients with coronary artery disease, but these benefits come at the expense of increased risk of bleeding when compared with aspirin monotherapy. Increased evidence showed that P2Y12 inhibitor monotherapy still maintain antiischemic efficacy while reducing the bleeding risk compared with DAPT. Therefore, the investigators performed this study to observe the efficacy of ticagrelor in comparison to clopidogrel in Chinese patients with stable CAD.

Timeline

Start
2019-07-02
Primary completion
2020-12-09
Completion
2020-12-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Clopidogrel Small molecule 75 mg —
Subject Ticagrelor Small molecule 90 mg —