Interactive Communication Technologies and Nicotine Replacement Therapy Sampling for Smokers

Summary

Brief advice combined with active referral to smoking cessation (SC) services increases quitting. We aim to strengthen the effect of combined intervention by using interactive communication technologies and nicotine replacement therapy sampling (NRT-S).

Timeline

Start

2019-08-19

Primary completion

2021-05-08

Completion

2021-09-30

Outcome

Missed primary endpoint

paper By intention-to-treat, the intervention group did not significantly increase validated abstinence at 6 months (3.9% vs 3.0%, OR=1.31; 95% CI: 0.57-3.04) PMID 36969982 ↗

paper Personalized behavioral support through mobile interventions plus NRT-S did not significantly improve abstinence in community smokers compared to text only messaging. PMID 36969982 ↗

Publications

• Guo N, Luk TT, Wu YS, Guo Z, Chu JCL, Cheung YTD, Chan CHH, Kwok TTO, Wong VYL, Wong CKH, Lee JJ, Kwok YK, Viswanath K, Lam TH, Wang MP. Effect of mobile interventions with nicotine replacement therapy sampling on long-term smoking cessation in community smokers: A pragmatic randomized clinical trial. Tob Induc Dis. 2023 Mar 24;21:44. doi: 10.18332/tid/160168. eCollection 2023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Nicotine	Unknown	2 mg	Oral
Subject	Nicotine	Unknown	4 mg	Oral
Subject	Nicotine	Unknown	14 mg	Oral
Subject	Nicotine	Unknown	21 mg	Oral

Indications