A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy
Summary
This is a study in adults with geographic atrophy, an advanced form of age-related macular degeneration. The purpose of this study is to find out how well different doses of BI 754132 are tolerated. The participants are in the study for about 4 months. During this time, they visit the study site about 10 times. Participants receive 1 injection of BI 754132 directly into one of the eyes affected by geographic atrophy. In this study, BI 754132 is given to humans for the first time. The doctors compare how well participants tolerate the different doses of BI 754132. The doctors also regularly check the general health of the participants.
Timeline
- Start
- 2019-07-26
- Primary completion
- 2022-08-09
- Completion
- 2022-08-09
Outcome
Outcome not reported
Stopped: “The trial was discontinued in the interests of patients considering benefit/risk balance.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BI 754132 | Unknown | 0.3 mg | Intravitreal |
| Subject | BI 754132 | Unknown | 1 mg | Intravitreal |
| Subject | BI 754132 | Unknown | 3 mg | Intravitreal |
| Subject | BI 754132 | Unknown | 6 mg | Intravitreal |