Air Versus Oxygen for Intermediate-Risk Pulmonary Embolism (AIRE)

Summary

The primary objective is to evaluate the efficacy of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism. The secondary objective is to evaluate the safety of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism.

Timeline

Start

2019-07-11

Primary completion

2022-04-24

Completion

2022-07-25

Publications

• Barrios D, Duran D, Rodriguez C, Moises J, Retegui A, Lobo JL, Lopez R, Chasco L, Jara-Palomares L, Muriel A, Otero-Candelera R, Ruiz-Artacho P, Monreal M, Bikdeli B, Jimenez D; Air vs Oxygen for Intermediate-Risk Pulmonary Embolism Investigators. Oxygen Therapy in Patients With Intermediate-Risk Acute Pulmonary Embolism: A Randomized Trial. Chest. 2024 Mar;165(3):673-681. doi: 10.1016/j.chest.2023.09.007. Epub 2023 Sep 16.

Drugs

Indications