Reduction of Occurence of Acute Kidney Injury (AKI) Through Administration of Glutamine

NCT04019184 ↗

Phase 3 Completed 64 enrolled University Hospital Muenster Fresenius Kabi · collab IZKF (Interdisciplinary Centre for Clinical Research (IZKF), Muenster) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The aim of this study is to evaluate whether the application of glutamine versus control in patients with high risk for AKI identified by biomarkers can reduce kidney damage after cardiac surgery.

Timeline

Start: 2019-07-18
Primary completion: 2020-02-13
Completion: 2020-05-13

Publications

Weiss R, Meersch M, Gerke M, Wempe C, Schafers M, Kellum JA, Zarbock A. Effect of Glutamine Administration After Cardiac Surgery on Kidney Damage in Patients at High Risk for Acute Kidney Injury: A Randomized Controlled Trial. Anesth Analg. 2023 Nov 1;137(5):1029-1038. doi: 10.1213/ANE.0000000000006288. Epub 2022 Nov 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Alanyl-glutamine	Peptide	0.5 g/kg	—

Reduction of Occurence of Acute Kidney Injury (AKI) Through Administration of Glutamine

Summary

Timeline

Publications

Drugs

Indications