drugset / Trial / NCT04045730

The Study of Gemcitabine Plus Nab-Paclitaxel in Combination With Pegvorhyaluronidase Alfa (PVHA; PEGPH20) and Pembrolizumab as Front-line Treatment for Metastatic Pancreatic Adenocarcinoma.

NCT04045730

Phase 2 Withdrawn Yale University
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label single arm phase 2 study for patients with metastatic pancreatic ductal adenocarcinoma who have not received any prior systemic therapies.

Timeline

Start
2019-11-15
Primary completion
2019-12-31
Completion
2021-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule
Subject Paclitaxel Small molecule
Subject Pegvorhyaluronidase Alfa Protein / enzyme biologic
Subject Pembrolizumab Monoclonal antibody