Vaginal Dinoprostone Administration Prior to an Intrauterine Device Insertion in Multiparous Women.

Phase 4 Completed 160 enrolled Cairo University

RandomizedParallel-groupQuadruple-blindTreatment

Summary

To investigate whether vaginal dinoprostone administered before intrauterine device (IUD) insertion reduces failed insertions, insertion-related complications, and pain in multiparous women.

Timeline

Start: 2019-08-30
Primary completion: 2020-01-10
Completion: 2020-01-30

Outcome

Met primary endpoint

paper The dinoprostone group had significantly lower pain scores during IUD insertion (34.8 ± 10.1 vs. 57.8 ± 11.8) PMID 32732105 ↗

Publications

Ashour AS, Nabil H, Yosif MF, Hussein M, Mageed A Allah AA, Mahmoud M, Abdou H, Kholaif K, Mohamed Kotb MM, El Sharkawy M, Abdelhakim AM, Ali AS, Nassar SA, Abbassy AH, Ghamry NK, Abdel-Latif AA, Taher A, El Mahy M. Effect of self-administered vaginal dinoprostone on pain perception during copper intrauterine device insertion in parous women: a randomized controlled trial. Fertil Steril. 2020 Oct;114(4):861-868. doi: 10.1016/j.fertnstert.2020.05.004. Epub 2020 Jul 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dinoprostone	Other / unclassified	3 mg	Other

Indications

No indication recorded.