drugset / Trial / NCT04046939

Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma

NCT04046939

Phase 2 Completed 534 enrolled Knopp Biosciences
RandomizedParallel-groupTriple-blindTreatment

Summary

This is a randomized, double-blind, placebo-controlled, parallel-group, dose-ranging, multi-center study to evaluate the clinical effects of oral administration of dexpramipexole for 12 weeks on peripheral blood eosinophil count in subjects with eosinophilic asthma.

Timeline

Start
2019-08-15
Primary completion
2020-12-03
Completion
2021-03-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexpramipexole Small molecule 37.5 mg Oral
Comparator Dexpramipexole Small molecule 75 mg Oral
Comparator Dexpramipexole Small molecule 150 mg Oral

Indications