drugset / Trial / NCT04053062

LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer

NCT04053062 ↗

Phase 1 Suspended 12 enrolled Bioray Laboratories Changhai Hospital · collab
NaSequentialOpen-labelTreatment

Summary

This is a single center, single arm Phase I study to establish the safety and efficacy of intravenously administered lentivirally transduced LIGHT-PSMA-specific CAR modified autologous T cells (PSMA-CART cells) in patients with CRPC.

Timeline

Start
2020-07-16
Primary completion
2022-05-15
Completion
2024-10-15

Outcome

Outcome not reported

Stopped: “Due to efficacy evaluation”

Drugs

EvaluationDrugModalityDoseRoute
Subject LIGHT-PSMA-CART Cell therapy 3e+06 cells/kg Intravenous
Subject LIGHT-PSMA-CART Cell therapy 6e+06 cells/kg Intravenous