drugset / Trial / NCT04053062
LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer
NaSequentialOpen-labelTreatment
Summary
This is a single center, single arm Phase I study to establish the safety and efficacy of intravenously administered lentivirally transduced LIGHT-PSMA-specific CAR modified autologous T cells (PSMA-CART cells) in patients with CRPC.
Timeline
- Start
- 2020-07-16
- Primary completion
- 2022-05-15
- Completion
- 2024-10-15
Outcome
Outcome not reported
Stopped: “Due to efficacy evaluation”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LIGHT-PSMA-CART | Cell therapy | 3e+06 cells/kg | Intravenous |
| Subject | LIGHT-PSMA-CART | Cell therapy | 6e+06 cells/kg | Intravenous |