Lofexidine for Management of Opioid Withdrawal With XR-NTX Treatment

Summary

This is an open-label pilot trial to evaluate the safety and tolerability of lofexidine in the management of opioid withdrawal symptoms while initiating outpatient treatment with naltrexone. The initiation procedure will be a flexible detoxification lasting 2 to 10 days concluding with the injection of XR-Naltrexone (Vivitrol). Vivitrol is a long-acting injection that contains enough medicine to last for one month blocking the effects of opioids.

Timeline

Start

2019-09-01

Primary completion

2021-01-29

Completion

2021-01-29

Drugs

Indications