Tulobuterol Patch in Pediatric Patients Undergoing Tonsillectomy

Completed 182 enrolled Seoul National University Hospital Chung-Ang University Hospital · collab Samsung Medical Center · collab Severance Hospital · collab

RandomizedParallel-groupQuadruple-blindPrevention

Summary

* Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event. * We tried to determine whether tulobuterol patch (transdermal bronchodilator) premedication decreases the risk of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy.

Timeline

Start: 2019-12-20
Primary completion: 2021-09-30
Completion: 2021-09-30

Publications

Kim EH, Lee SH, Kim JK, Park YH, Kang P, Park JB, Ji SH, Jang YE, Lee JH, Kim JT, Kim HS. Effect of Tulobuterol Patch Versus Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: A Randomized Controlled Trial. Anesth Analg. 2023 Jun 1;136(6):1067-1074. doi: 10.1213/ANE.0000000000006355. Epub 2023 May 19.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tulobuterol	Small molecule	1 mg	Other

Indications

No indication recorded.