drugset / Trial / NCT04064190

Vactosertib with Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibition

NCT04064190

NaSingle-groupOpen-labelTreatment

Summary

This is Phase 2, open label, non randomized single arm study to determine whether the administration of vactosertib with durvalumab will provide meaningful increases in the Overall Response Rate (ORR) in patients with urothelial cancers that fail to achieve a response with anti-PD-1/PD-L1 based regimens

Timeline

Start
2019-12-13
Primary completion
2023-12-30
Completion
2024-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg Intravenous
Subject Vactosertib Small molecule 300 mg Oral

Indications