drugset / Trial / NCT04073589

Efgartigimod Co-administered Subcutaneously With rHuPH20 in Healthy Subjects

NCT04073589

Phase 1 Completed 33 enrolled argenx
RandomizedParallel-groupOpen-labelOther

Summary

The aim of this trial is to investigate the pharmacodynamic (PD), pharmacokinetic (PK), safety, tolerability, and immunogenicity of efgartigimod co-administered with rHuPH20, and to measure the time to inject the full dose of investigational medicinal product (IMP) of different dose levels of efgartigimod co-administered with a fixed concentration of rHuPH20 by the subcutaneous (SC) route of administration in healthy adult male subjects.

Timeline

Start
2019-07-17
Primary completion
2019-09-26
Completion
2019-09-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Efgartigimod Alfa Protein / enzyme biologic Subcutaneous
Background rHuPH20 Protein / enzyme biologic Subcutaneous

Indications

No indication recorded.