drugset
drugset / Trial / NCT04073849

CD71 in Dried Blood Spots in Healthy Males

NCT04073849 ↗

Phase 0 Completed 24 enrolled Sports Medicine Research and Testing Laboratory
RandomizedParallel-groupSingle-blindOther

Summary

Understand the effect of recombinant EPO (rEPO) boosting and microdosing on the hematological module of the Athlete Biological Passport (ABP) * Measure the change in CD71 longitudinally in subjects from both cohorts * Assess whether rEPO administration can be detected in a dried blood spot (DBS) using recent advances in analytical methodologies * Compare windows of rEPO detection using both Athlete Biological Passport models and direct detection using analytical methods in urine, blood, and DBS

Timeline

Start
2019-07-15
Primary completion
2020-11-15
Completion
2020-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator epoetin alfa Protein / enzyme biologic 40 iu/kg Subcutaneous
Comparator epoetin alfa Protein / enzyme biologic 900 iu Subcutaneous

Indications

No indication recorded.