drugset / Trial / NCT04074473

Impact of Nonselective Beta-blocker on Acute Kidney Injury in Cirrhotic Patients With Esophageal Varices

NCT04074473

Phase 4 Unknown 170 enrolled Taipei Veterans General Hospital, Taiwan
RandomizedParallel-groupSingle-blindTreatment

Summary

We will include patients with EV and EVB. They will be randomized to EVL vs. NSBB for primary prevention And EVL+long-term NSBB vs. EVL+short-term NSBB for secondary prevention. 150 patients will be included in a 3-year period. Primary end-points are formation/progression of ascites, acute kidney injury and survival. The other outcomes such as bleeding, rebleeding, infection and other risk factors will be also analyzed.

Timeline

Start
2015-04-13
Primary completion
2015-11-05
Completion
2020-07-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propranolol Small molecule 10 mg