drugset / Trial / NCT04079296

A Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS)

NCT04079296 ↗

Phase 1/2 Completed 43 enrolled Astellas Pharma Global Development, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study was to evaluate the safety and tolerability and to determine the recommended phase 2 dose (RP2D) and/or the maximum tolerated dose (MTD) of ASP7517. This study also evaluated the clinical response of ASP7517 as well as other measures of anticancer activity of ASP7517.

Timeline

Start
2019-09-19
Primary completion
2023-04-21
Completion
2023-04-21

Drugs

EvaluationDrugModalityDoseRoute
Subject ASP7517 Unknown 1e+06 unknown Intravenous
Subject ASP7517 Unknown 1e+07 unknown Intravenous
Subject ASP7517 Unknown 1e+08 unknown Intravenous