drugset / Trial / NCT04082858
Ketamine Interleaved With Electroconvulsive Therapy for Depression
RandomizedParallel-groupQuadruple-blindHealth-services research
Summary
Pragmatic, randomised, controlled, parallel group, pilot clinical trial of ketamine vs. midazolam interleaved with electroconvulsive therapy (ECT) as an adjunctive treatment for a major depressive episode. The main purpose of the pilot study is to assess trial processes to help inform a future definitive trial.
Timeline
- Start
- 2020-01-06
- Primary completion
- 2020-06-03
- Completion
- 2020-06-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 0.5 mg/kg | — |
| Comparator | Midazolam | Small molecule | 0.045 mg/kg | — |