drugset / Trial / NCT04086238

Effect of Food on the Pharmacokinetics of Decitabine/Tetrahydrouridine Combination Capsules in Healthy Adult Subjects

NCT04086238

Phase 1 Completed 46 enrolled EpiDestiny, Inc.
RandomizedCrossoverOpen-labelOther

Summary

This study is to investigate the effect of a high fat meal on the pharmacokinetics of decitabine and THU in healthy adults when administered as a modified release formulation of the 2 drugs in combination.

Timeline

Start
2019-10-08
Primary completion
2019-11-21
Completion
2019-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Decitabine Small molecule 5 mg Oral
Subject Tetrahydrouridine Small molecule 250 mg Oral

Indications

No indication recorded.