drugset / Trial / NCT04089631

Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

NCT04089631 ↗

Phase 3 Unknown 4812 enrolled Technical University Dresden
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive for postoperative circulating tumour DNA with vs. without capecitabine.

Timeline

Start
2020-06-26
Primary completion
2023-06
Completion
2026-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1000 mg/m2 Oral
Subject Capecitabine Small molecule 1250 mg/m2 Oral

Indications