drugset / Trial / NCT04090697

Use of Oxandrolone to Promote Growth in Infants With HLHS

NCT04090697

Phase 1/2 Terminated 34 enrolled Carelon Research
RandomizedParallel-groupOpen-labelSupportive care

Summary

The primary aim of this study is to determine if clinically relevant doses of buccally administered oxandrolone are safe and tolerable in neonates with hypoplastic left heart syndrome (HLHS) or other single right ventricular anomalies who have undergone a Norwood procedure. The secondary aim is to evaluate the efficacy of buccally administered oxandrolone in improving objective indices of growth and nutrition in neonates who have undergone a Norwood procedure.

Timeline

Start
2019-12-20
Primary completion
2023-09-19
Completion
2023-09-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxandrolone Small molecule 0.1 mg/kg Other
Subject Oxandrolone Small molecule 0.15 mg/kg Other