drugset / Trial / NCT04096716
Mapping Draining Lymph Nodes in CNS Malignancies
Phase 1
Terminated
14 enrolled
Washington University School of Medicine
Lloyd J. Old STAR Program · collab
Non-randomizedParallel-groupOpen-labelDiagnostic
Summary
The purpose of this research study is to determine whether the lymph nodes that drain a brain tumor can be detected by imaging after injection of a substance called Tc-99m tilmanocept directly into the brain tissue around the tumor. Tc-99m tilmanocept is a radioactive substance that is used to find lymph nodes by injecting it and then scanning the body with a device that can trace its radioactivity. In this study, the investigators are looking to see how long it takes the Tc-99m tilmanocept to travel from the tumor to the lymph nodes. The investigators will be using it to map lymph nodes as they relate to specific brain areas.
Timeline
- Start
- 2019-12-03
- Primary completion
- 2022-04-30
- Completion
- 2022-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Technetium Tc 99m Tilmanocept | Diagnostic / imaging agent | 0.3 ml | Other |
| Subject | Technetium Tc 99m Tilmanocept | Diagnostic / imaging agent | 0.5 ml | Other |