drugset / Trial / NCT04097509

Effects of Platelet Concentrates on Palatal Wound Healing

NCT04097509 ↗

Completed 36 enrolled Inonu University
RandomizedParallel-groupDouble-blindSupportive care

Summary

Platelet concentrates used in palatal wound healing have been reported to accelerate wound healing and reduce postoperative patient discomfort. The use of elet platelet rich fibrin '(PRF) in the palatal donor site after FGG surgery has been shown to provide significant benefits in terms of wound healing parameters and postoperative comfort. In a study using a platelet rich plasma (PRP) with a different platelet concentration, PRP was found to accelerate wound healing and shorten the healing time. In another study using titanium-prepared platelet rich fibrin (T-PRF) for palatal wound healing, it accelerated the wound healing process and reached the initial level of soft tissue thickness in the donor region at the end of 6 months. In the literature, there are few studies using platelet concentrates in palatal wound healing and only some concentrates (PRP, PRF, T-PRF) are used. The aim of this study is to compare the effects of injectable platelet rich fibrin (i-PRF), which are autologous fibrin glue (AFG) and injectable platelet concentrates, on palatal wound healing. The findings obtained from this study will contribute to the literature in determining the product and method that will provide optimal postoperative patient comfort and wound healing.

Timeline

Start
2018-05-01
Primary completion
2019-02-10
Completion
2019-06-10

Drugs

EvaluationDrugModalityDoseRoute
Subject autologous fibrin glue Unknown — —
Subject injectable platelet rich fibrin Unknown — —