drugset / Trial / NCT04103476
Advancing Postmenopausal Preventive Therapy
Phase 2
Active not recruiting
385 enrolled
University of Southern California
National Institute on Aging (NIA) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Advancing Postmenopausal Preventive Therapy (APPT) is a randomized, double-blinded, placebo-controlled trial designed to determine the effects of tissue selective estrogen complex (TSEC) therapy on the progression of subclinical atherosclerosis and cognitive decline in 360 healthy postmenopausal women.
Timeline
- Start
- 2021-04-13
- Primary completion
- 2026-10-31
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bazedoxifene | Other / unclassified | 20 mg | Oral |
| Subject | conjugated estrogens | Other / unclassified | 0.45 mg | Oral |