drugset / Trial / NCT04103489

The Use of Eculizumab in HELLP Syndrome

NCT04103489

NaSingle-groupOpen-labelTreatment

Summary

This research study is being performed to see if women diagnosed with early preterm Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP) syndrome (estimated gestational ages of 23-30 weeks) benefit from a medication called eculizumab (ECU). This drug blocks a part of the immune system called complement. By blocking this part of the immune system, eculizumab may stop or reverse the progression of the HELLP syndrome disease. The investigators will also look to see if this drug is effective and benefits both the mother and fetus.

Timeline

Start
2021-02-23
Primary completion
2023-08-31
Completion
2023-09-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Eculizumab Monoclonal antibody

Indications