drugset / Trial / NCT04108377

Phosphodiesterase 4 Inhibitor, Roflumilast, and the Effects of Inhibition in Severe Asthma

NCT04108377

Phase 1 Terminated 5 enrolled University of California, Davis
RandomizedParallel-groupDouble-blindTreatment

Summary

This study evaluates the effects of roflumilast on restoring response β2 adrenoreceptor agonists in low T2, obese asthmatics. One group of participants will receive roflumilast for 3 months, while the other will receive a placebo.

Timeline

Start
2019-01-21
Primary completion
2022-12-11
Completion
2023-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Roflumilast Small molecule 500 ug Oral

Indications