drugset / Trial / NCT04109859

Effect of Methylene Blue on Perioperative Organ Function in Patients With Obstructive Jaundice

NCT04109859

Phase 1 Unknown 64 enrolled Jiaolin Ning,MD
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Increased production of vasodilating substances such as NO plays an important role in the development of vasoplegic syndrome caused by obstructive jaundice.Methylene blue plays a role in raising blood pressure by inhibiting the vasodilator Nitric Oxide (NO)

Timeline

Start
2019-04-01
Primary completion
2021-01-21
Completion
2021-01-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylene Blue Diagnostic / imaging agent 0.5 mg/kg Intravenous

Indications