drugset / Trial / NCT04113187
Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients
Phase 3
Terminated
15 enrolled
University Hospital, Bordeaux
AMRO-HHT-France - Association Maladie de Rendu-Osler · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic disorder of angiogenesis associated with disabling epistaxis. Management of these nose bleedings requires more effective treatment. Propranolol, a beta-blocker, is a potentially useful therapeutic considering its anti-angiogenic properties. Our objective is to explore the efficacy of propranolol, three months after its introduction, on the cumulative duration of epistaxis in HHT patients.
Timeline
- Start
- 2020-06-23
- Primary completion
- 2022-05-19
- Completion
- 2022-05-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propranolol | Small molecule | 40 mg | Oral |