drugset / Trial / NCT04113187

Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients

NCT04113187

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic disorder of angiogenesis associated with disabling epistaxis. Management of these nose bleedings requires more effective treatment. Propranolol, a beta-blocker, is a potentially useful therapeutic considering its anti-angiogenic properties. Our objective is to explore the efficacy of propranolol, three months after its introduction, on the cumulative duration of epistaxis in HHT patients.

Timeline

Start
2020-06-23
Primary completion
2022-05-19
Completion
2022-05-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Propranolol Small molecule 40 mg Oral