Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers

Summary

This study will evaluate the mechanistic basis for the analgesic effects of GSK3858279 in humans by using a battery of experimental pain assessments in healthy participants. This will be placebo-controlled, three-period two-treatment crossover study. In each period, participants will receive either GSK3858279 or placebo in a 1:1 ratio. Only healthy male participants will be enrolled into the study. The duration of the study will be approximately 6 months.

Timeline

Start

2019-10-15

Primary completion

2021-09-16

Completion

2021-09-16

Outcome

Outcome not reported

Stopped: “This study was terminated due to meeting protocol defined futility.”

Drugs

Indications

No indication recorded.