drugset / Trial / NCT04121975

CCRT Combined With Endostar for the Treatment of Locally Advanced Cervical Cancer

NCT04121975

Phase 2 Unknown 82 enrolled Zhejiang Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

This was a prospective, single arm, phase 2 trial. Adult Patients with histologically confirmed locally advanced cervical cancer were enrolled to receive the treatment of concurrent chemoradiotherapy combined with Endostar. The primary endpoint was progression-free survival (PFS) rate at 1 year. The secondary endpoints were PFS, overall survival (OS) and safety.

Timeline

Start
2019-08-01
Primary completion
2021-08
Completion
2022-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Endostar Protein / enzyme biologic 30 mg
Background Cisplatin Other / unclassified 30 mg/m2
Background Cisplatin Other / unclassified 40 mg/m2

Indications