drugset

drugset / Trial / NCT04126083

Lofexidine for Adults Undergoing Lumbar Spine Surgery

NCT04126083 ↗

Phase 4 Completed 6 enrolled Mayo Clinic USWM, LLC (dba US WorldMeds) · collab

NaSingle-groupOpen-labelTreatment

Summary

The primary objective is to investigate the effects of lofexidine in adults undergoing opioid tapering prior to elective lumbar spine surgery.

Timeline

Start: 2019-09-01
Primary completion: 2021-04-15
Completion: 2021-04-15

Publications

Background Fishman M, Tirado C, Alam D, Gullo K, Clinch T, Gorodetzky CW; CLEEN-SLATE Team. Safety and Efficacy of Lofexidine for Medically Managed Opioid Withdrawal: A Randomized Controlled Clinical Trial. J Addict Med. 2019 May/Jun;13(3):169-176. doi: 10.1097/ADM.0000000000000474.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lofexidine	Small molecule	0.54 mg	Oral

Indications