drugset / Trial / NCT04130282
VAC077: Safety and Immunogenicity of the Pfs25-IMX313/Matrix-M Vaccine
NaSingle-groupOpen-labelPrevention
Summary
This is an open label, single-site, first-in-human, Phase Ia study to assess safety and immunogenicity of the Plasmodium falciparum malaria vaccine candidate Pfs25-IMX313 in Matrix-M1 adjuvant in healthy adults living in the UK Volunteers will receive 3 doses of vaccine over 2 months and will be followed up for approximately 8 months.
Timeline
- Start
- 2019-09-27
- Primary completion
- 2020-09-22
- Completion
- 2020-09-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pfs25-IMX313 | Vaccine | 10 ug | — |
| Background | Matrix-M1 | Other / unclassified | 50 ug | — |