drugset / Trial / NCT04130282

VAC077: Safety and Immunogenicity of the Pfs25-IMX313/Matrix-M Vaccine

NCT04130282

Phase 1 Terminated 1 enrolled University of Oxford
NaSingle-groupOpen-labelPrevention

Summary

This is an open label, single-site, first-in-human, Phase Ia study to assess safety and immunogenicity of the Plasmodium falciparum malaria vaccine candidate Pfs25-IMX313 in Matrix-M1 adjuvant in healthy adults living in the UK Volunteers will receive 3 doses of vaccine over 2 months and will be followed up for approximately 8 months.

Timeline

Start
2019-09-27
Primary completion
2020-09-22
Completion
2020-09-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Pfs25-IMX313 Vaccine 10 ug
Background Matrix-M1 Other / unclassified 50 ug