drugset / Trial / NCT04131231
Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a prospective, open-label , multicenter randomized controlled trial, with 248 cases in 50 centers planned for a period of 2 years. The aim of the study is to evaluate the safety and effectiveness of microparticles packaging chemotherapeutic drugs (MPCD) therapy on the treatment of malignant pleural effusion (MPE) in patients with advanced lung cancer or breast cancer.
Timeline
- Start
- 2019-10-15
- Primary completion
- 2021-01-15
- Completion
- 2021-06-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methotrexate | Small molecule | — | Other |
| Comparator | Recombinant Human Interleukin-2 | Protein / enzyme biologic | 2e+06 iu | Other |