drugset / Trial / NCT04132427
MTT for Children With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Pitt Hopkins Syndrome (PTHS) and gastrointestinal problems similar to Irritable Bowel Syndrome (IBS). MTT involves a combination of 10 days of oral vancomycin (an antibiotic to kill pathogenic bacteria), followed by a bowel cleanse, followed by 12 weeks of Fecal Microbiota (FM).
Timeline
- Start
- 2019-09-30
- Primary completion
- 2022-03-17
- Completion
- 2022-04-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fecal Microbiota | Other / unclassified | — | Oral |
| Subject | Vancomycin | Other / unclassified | — | Oral |
| Background | Magnesium Citrate | Unknown | — | Oral |