drugset / Trial / NCT04134468

MRI Effects of Pegvorhyaluronidase Alfa (PEGPH20) in Pancreatic Ductal Adenocarcinoma

NCT04134468

NaSingle-groupOpen-labelTreatment

Summary

This research study is being conducted to determine the effects of PEGPH20 plus chemotherapy treatment on the MRI characteristics of locally advanced pancreatic cancer patient tumors. Subjects will received Gemcitabine, Abraxane and PEGPH20.

Timeline

Start
2020-01
Primary completion
2021-02-11
Completion
2022-11-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Pegvorhyaluronidase Alfa Protein / enzyme biologic 3 ug/kg Intravenous
Background Gemcitabine Small molecule 1000 mg/m2 Intravenous
Background Paclitaxel Small molecule 125 mg/m2 Intravenous