drugset
drugset / Trial / NCT04138836

Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects

NCT04138836 ↗

Phase 1 Completed 48 enrolled Bridge Biotherapeutics, Inc. KCRN Research, LLC · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Study to determine the effect of multiple-dose BBT-877 on the single-dose pharmacokinetics of midazolam, the safety and tolerability of a single dose of BBT-877 administered alone and with multiple doses of itraconazole, and the effect of multiple-dose esomeprazole on the single-dose pharmacokinetics of BBT-877, in healthy adult subjects.

Timeline

Start
2019-09-17
Primary completion
2019-11-04
Completion
2019-11-04

Drugs

EvaluationDrugModalityDoseRoute
Subject BBT-877 Unknown — Oral
Subject Esomeprazole Small molecule — Oral
Subject Itraconazole Small molecule — Oral
Subject Midazolam Small molecule — Oral

Indications

No indication recorded.