drugset / Trial / NCT04144023
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
NaSingle-groupOpen-labelTreatment
Summary
This phase Ib trial studies the side effects and best dose of a vaccine called H2NVAC before surgery in treating patients with HER2 expressing ductal carcinoma in situ. H2NVAC is a vaccine designed to stimulate specialized white blood cells in hopes of increasing immune response and protecting against breast cancer.
Timeline
- Start
- 2019-06-27
- Primary completion
- 2027-12-31
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | H2NVAC | Vaccine | — | Intrathecal |
| Background | sargramostim | Protein / enzyme biologic | — | Intrathecal |