drugset / Trial / NCT04149990
Angiotensin-Neprilysin Inhibition in Diastolic Dysfunction After AMI
Phase 2
Terminated
51 enrolled
Jacob Moller
Danish Heart Foundation · collabOdense University Hospital · collabRigshospitalet, Denmark · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study examines the effect of Entresto on central hemodynamic parameters during exercise in patients with diastolic dysfunction following acute myocardial infarction. Half of the patients will receive Entresto and the other half will receive placebo.
Timeline
- Start
- 2018-10-12
- Primary completion
- 2022-07-06
- Completion
- 2023-06-06
Outcome
Outcome not reported
Stopped (Enrollment): “Low recruitment”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sacubitril | Small molecule | 97 mg | — |
| Comparator | Valsartan | Unknown | 103 mg | — |