drugset / Trial / NCT04154488
A Study of Mavorixafor in Participants With Congenital Neutropenia and Chronic Idiopathic Neutropenia Disorders
NaSingle-groupOpen-labelTreatment
Summary
This is a 2-part study of mavorixafor in participants diagnosed with chronic neutropenia. The main goal of Part 1 (Phase 1b) is to help researchers learn more about how the investigational medicine, mavorixafor, impacts people living with chronic neutropenia (including congenital, idiopathic, and cyclic). In Part 2 (Phase 2), the safety and tolerability of chronic dosing of mavorixafor will be evaluated in a larger participant population and the impact of 6-month chronic dosing of mavorixafor on participant neutropenia.
Timeline
- Start
- 2021-10-16
- Primary completion
- 2024-08-27
- Completion
- 2024-08-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mavorixafor | Small molecule | 200 mg | Oral |
| Subject | Mavorixafor | Small molecule | 400 mg | Oral |