Investigational Microbiota Restoration Therapeutic for Hepatic Encephalopathy

Summary

Individuals with cirrhosis are likely to develop overt hepatic encephalopathy for which diagnostic modalities and treatment options are limited. The purpose of this study is to determine if individuals with cirrhosis who experience hepatic encephalopathy would benefit from investigational microbiota restoration therapy due to their inherent cognitive alterations. Analysis for a correlation between changes in microbiome composition and specific blood biomarkers could allow for earlier diagnosis of HE which could then be treated earlier and with novel treatments.

Timeline

Start

2021-03-01

Primary completion

2023-07-30

Completion

2023-07-30

Outcome

Outcome not reported

Stopped (Enrollment): “Unable to recruit participants”

Drugs

Indications