drugset / Trial / NCT04156815

Treatment of Acne Vulgaris Using NAFL in Combination With Isotretinoin and Pricking Blood Therapy

NCT04156815 ↗

Completed 60 enrolled xjpfW
RandomizedFactorialDouble-blindTreatment

Summary

BACKGROUND Isotretinoin remains one of the first line medications for moderate-to-severe acne vulgaris (AV) but its side effect is a major concern for Asian patients. OBJECTIVE Investigators aimed to evaluate the efficacy and safety of the 1,565 nm non-ablative fractional laser (NAFL) in combination with isotretinoin and pricking blood therapy (PBT) for treatment of AV. METHODS A retrospective analysis of 60 patients with moderate-to-severe AV was performed. Four groups (n=15) were evaluated: 1,565nm NAFL alone, oral isotretinoin alone, double therapy (NAFL + isotretinoin) and triple therapy (NAFL + isotretinoin + PBT).

Timeline

Start
2018-07-05
Primary completion
2018-10-05
Completion
2018-10-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Oral isotretinoin Unknown 0.5 mg/kg Oral

Indications