drugset / Trial / NCT04166058

Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C

NCT04166058

Phase 3 Completed 381 enrolled AbbVie Ironwood Pharmaceuticals, Inc. · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

LIN-MD-66 is a Phase 3 open-label study with 24 weeks (Functional Constipation participants) or 52 weeks (Irritable bowel syndrome with constipation participants) of linaclotide exposure that will enroll pediatric participants (6-17 years of age) with FC or IBS-C who completed study intervention in studies LIN-MD-62, LIN-MD-63, or LIN-MD-64 based on the individual study criteria.

Timeline

Start
2019-11-19
Primary completion
2025-06-05
Completion
2025-06-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Linaclotide Peptide 72 ug Oral
Comparator Linaclotide Peptide 145 ug Oral
Comparator Linaclotide Peptide 290 ug Oral