drugset / Trial / NCT04167982

Efficacy and Safety of Painless 5-aminolevulinic Acid Photodynamic Therapy for Moderate and Severe Acne Vulgaris

NCT04167982

RandomizedParallel-groupSingle-blindTreatment

Summary

This study is being done to compare a new, continuous illumination and short Incubation time regimen of 5-aminolevulinic acid photodynamic therapy (painless ALA- PDT) to low-dose and conventional dose of oral isotretinoin for treatment of moderate or severe acne vulgaris. The hypothesis is that the painless ALA- PDT will be equally or more efficacious as oral isotretinoin, and taking effect more quickly with less adverse effect.

Timeline

Start
2020-03-28
Primary completion
2022-11-30
Completion
2022-11-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Isotretinoin Other / unclassified 0.2 mg/kg Oral
Comparator Isotretinoin Other / unclassified 0.5 mg/kg Oral

Indications