drugset / Trial / NCT04170426

Autologous Adipose-derived Stem Cells (AdMSCs) for Rheumatoid Arthritis

NCT04170426 ↗

Phase 1/2 Not yet recruiting 54 enrolled Celltex Therapeutics Corporation
RandomizedSequentialQuadruple-blindTreatment

Summary

This is an investigational new drug clinical trial for combined Phase 1 dose escalation study and Phase 2a randomized, placebo controlled and double blinded study using intravenous injection of autologous adipose stem cells (Celltex AdMSCs) for rheumatoid arthritis patients. All subjects are monitored for safety (adverse events/severe adverse events) and evaluated for RAPID3, DAS28 and ACR20 regarding AdMSCs up to 52 weeks study duration.

Timeline

Start
2023-12
Primary completion
2024-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Autologous adipose derived stem cells Cell therapy 2e+06 cells/kg Intravenous
Subject Autologous adipose derived stem cells Cell therapy 2.86e+06 cells/kg Intravenous

Indications