drugset / Trial / NCT04170426
Autologous Adipose-derived Stem Cells (AdMSCs) for Rheumatoid Arthritis
RandomizedSequentialQuadruple-blindTreatment
Summary
This is an investigational new drug clinical trial for combined Phase 1 dose escalation study and Phase 2a randomized, placebo controlled and double blinded study using intravenous injection of autologous adipose stem cells (Celltex AdMSCs) for rheumatoid arthritis patients. All subjects are monitored for safety (adverse events/severe adverse events) and evaluated for RAPID3, DAS28 and ACR20 regarding AdMSCs up to 52 weeks study duration.
Timeline
- Start
- 2023-12
- Primary completion
- 2024-12
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Autologous adipose derived stem cells | Cell therapy | 2e+06 cells/kg | Intravenous |
| Subject | Autologous adipose derived stem cells | Cell therapy | 2.86e+06 cells/kg | Intravenous |