drugset / Trial / NCT04177498

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

NCT04177498

NaSingle-groupOpen-labelTreatment

Summary

This pilot trial studies how rigsertib sodium works in treating patients with Recessive Dystrophic Epidermolysis bullosa (RDEB) with locally advanced Squamous Cell Carcinoma (SCC). Rigosertib may selectively target Epidermolysis bullosa (EB) cancer cells while leaving normal EB cells unaffected.

Timeline

Start
2021-08-24
Primary completion
2025-05-05
Completion
2025-05-05

Drugs

EvaluationDrugModalityDoseRoute
Subject rigosertib Small molecule Oral