drugset / Trial / NCT04177498
Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC
NaSingle-groupOpen-labelTreatment
Summary
This pilot trial studies how rigsertib sodium works in treating patients with Recessive Dystrophic Epidermolysis bullosa (RDEB) with locally advanced Squamous Cell Carcinoma (SCC). Rigosertib may selectively target Epidermolysis bullosa (EB) cancer cells while leaving normal EB cells unaffected.
Timeline
- Start
- 2021-08-24
- Primary completion
- 2025-05-05
- Completion
- 2025-05-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | rigosertib | Small molecule | — | Oral |