drugset / Trial / NCT04177875

Neoadjuvant Chemoradiotherapy Combined With PD-1 Antibody in Locally Advanced Esophageal Cancer

NCT04177875 ↗

Phase 2 Unknown 44 enrolled Tongji Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study will evaluate the safety and feasibility of preoperative immune checkpoint therapy with concurrent Chemoradiotherapy in patients with locally advanced esophageal squamous cell carcinoma. And this study will provide valuable information for further clinical trials of preoperative Teripalimab and other immune checkpoint therapy in esophageal cancer treatment.

Timeline

Start
2019-05-01
Primary completion
2021-04-30
Completion
2022-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Teripalimab Monoclonal antibody 3 mg/kg —
Subject Teripalimab Monoclonal antibody 240 mg —

Indications