drugset / Trial / NCT04180137

Management of Endothelial Dysfunction in Patients With Chronic Venous Insufficiency After Endovenous Surgical Procedure

NCT04180137

RandomizedParallel-groupOpen-labelBasic science

Summary

Endothelial dysfunction is assessed in patients with chronic venous insufficiency of lower limbs (grade C4 according to C - clinical manifestations, E - etiologic factors, A - anatomic distribution of disease, and P - underlying pathophysiologic findings (CEAP) classification) prior to and after endovenous surgical procedure, i.e. endovenous laser ablation of great saphenous vein, microphlebectomy of varicose branches. Two treatment groups (with and without additional pharmacotherapy) are compared.

Timeline

Start
2019-11-28
Primary completion
2020-12-31
Completion
2021-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sulodexide Other / unclassified 250 unknown