drugset / Trial / NCT04186988
[18F]-AraG for the Detection of T-Cell Activation in Advanced Non-small Cell Lung Cancer Patients Undergoing PD-1/PD-L1-Directed Therapy
Phase 0
Withdrawn
University of California, Davis
CellSight Technologies, Inc. · collabNational Cancer Institute (NCI) · collab
NaSingle-groupOpen-labelDiagnostic
Summary
This trial studies how well \[18F\]-AraG works in detecting T-cell activation in patients with non-small cell lung cancer that has spread to other places in the body (advanced), who are undergoing PD-1/PD-L1-directed therapy. \[18F\]-AraG is a "radiotracer" which attaches to immune cells directed at the cancer and shines a light that can be seen using a special camera, called a "positron emission tomography" or "PET" scanner. \[18F\]-AraG may improve the ability to detect a response of the cancer in the body to immunotherapy.
Timeline
- Start
- 2019-11-05
- Primary completion
- 2020-03-12
- Completion
- 2020-03-12
Outcome
Outcome not reported
Stopped (Enrollment): “Unable to recruit to study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluorine F 18 Ara-G | Diagnostic / imaging agent | — | Intravenous |