drugset / Trial / NCT04186988

[18F]-AraG for the Detection of T-Cell Activation in Advanced Non-small Cell Lung Cancer Patients Undergoing PD-1/PD-L1-Directed Therapy

NCT04186988 ↗

NaSingle-groupOpen-labelDiagnostic

Summary

This trial studies how well \[18F\]-AraG works in detecting T-cell activation in patients with non-small cell lung cancer that has spread to other places in the body (advanced), who are undergoing PD-1/PD-L1-directed therapy. \[18F\]-AraG is a "radiotracer" which attaches to immune cells directed at the cancer and shines a light that can be seen using a special camera, called a "positron emission tomography" or "PET" scanner. \[18F\]-AraG may improve the ability to detect a response of the cancer in the body to immunotherapy.

Timeline

Start
2019-11-05
Primary completion
2020-03-12
Completion
2020-03-12

Outcome

Outcome not reported

Stopped (Enrollment): “Unable to recruit to study.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Fluorine F 18 Ara-G Diagnostic / imaging agent — Intravenous