Cefepime vs Ceftazidime as Empirical Therapy for Neutropenic Fever

Summary

Empirical antibiotic therapy has been known to reduce the mortality and morbidity rate in neutropenic fever. Until now, ceftazidime was the first line choice of neutropenic fever. However, resistance against ceftazidime has been reported. Several countries have reported cefepime in reducing fever and shorten the length of hospitalization better than ceftazidime. This study is aimed to compare the effectivity of ceftazidime and cefepime to reduce fever and to increase the absolute neutrophils count (ANC) in the first 72 hours.

Timeline

Start

2019-03-01

Primary completion

2019-07-31

Completion

2019-07-31

Drugs

Indications