Local Pilocarpine for Relieving Dry Mouth

Summary

The investigators intended for this study to deliver the "proof-of-concept" that locally administered pilocarpine drops in two doses are effective in a population of elderly (aged ≥ 70 years) with xerostomia at the expense of limited adverse events. To this end, the study aims to quantify the effect size of pilocarpine in two different dosages. In case the investigators observe clinically meaningful changes in xerostomia through measured NRS, a sufficiently-powered RCT will be prepared to compare pilocarpine to placebo.

Timeline

Start

2019-04-01

Primary completion

2019-12-01

Completion

2020-01-31

Drugs

Indications

No indication recorded.